THY-LIN 10

Thymulin is a synthetic nonapeptide (Pyr-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn) originally identified as a hormone produced by thymic epithelial cells. It is a metallopeptide that requires zinc in a 1:1 molar ratio to achieve biological activity. Thymulin functions as a key mediator of T-lymphocyte differentiation and maturation, operating through specific high-affinity receptors to modulate the immune response. Research applications include investigations into neuroendocrine-immune interactions, the regulation of pro-inflammatory cytokines (such as TNF-alpha and IL-6), and the modulation of the hypothalamic-pituitary-adrenal (HPA) axis under physiological stress.

Properties

• Amino Acid Sequence: Pyr-Ala-Lys-Ser-Gln-Gly-Gly-Ser-Asn
• Chemical Formula: C33H54N12O15
• Molar Mass: 858.85 g/mol
• CAS Number: 63958-90-7
• Synonyms: Nonathymulin, Serum Thymic Factor (FTS), Facteur Thymique Sérique