P41 10

Analytical Reagent PT-141 is a synthetic cyclic peptide analog of α-melanocyte-stimulating hormone (α-MSH) and a de-esterified metabolite of MT-II. This reagent is utilized in laboratory settings to investigate melanocortin receptor signaling, specifically targeting the MC3R and MC4R pathways within the central nervous system. Research focus primarily involves the interrogation of neuroendocrine pathways, the study of dopamine-melanocortin interactions, and the investigation of signal transduction in autonomic research models.

Technical Properties

• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH
• Molecular Formula: C50H68N14O10
• Molar Mass: 1025.16 g/mol
• CAS Number: 189691-06-3