KPV

KPV is a tripeptide (Lys-Pro-Val) representing the C-terminal fragment of the endogenous neuropeptide alpha-Melanocyte Stimulating Hormone (alpha-MSH). It is characterized by potent anti-inflammatory and antimicrobial properties, operating independently of the melanocortin receptors (MCRs) typically associated with pigmentation. KPV functions by modulating the NF-kappaB signaling pathway and inhibiting the expression of pro-inflammatory cytokines. Research applications include investigations into inflammatory bowel disease (IBD) models, wound healing acceleration, and the regulation of dermatological inflammatory responses.

Properties

• Amino Acid Sequence: Lys-Pro-Val
• Chemical Formula: C16H30N4O4
• Molar Mass: 342.43 g/mol
• CAS Number: 67727-97-3