D$IP 10

DSIP (Delta Sleep-Inducing Peptide) is a naturally occurring neuropeptide (Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu) first isolated from the cerebral venous blood of rabbits in an induced state of sleep. It is a non-apeptide that crosses the blood-brain barrier and interacts with various neuromodulatory pathways, including the glutamatergic and GABAergic systems. DSIP is characterized by its ability to induce delta-wave EEG activity and modulate endocrine responses to stress. Research applications include investigations into sleep-wake cycle regulation, circadian rhythm homeostasis, and the modulation of corticotropin levels.

Properties

• Amino Acid Sequence: Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu
• Chemical Formula: C35H48N10O15
• Molar Mass: 848.81 g/mol
• CAS Number: 62568-57-4