Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from a fragment of the adrenocorticotropic hormone (ACTH 4-10). It is characterized by its neuroprotective and neurorestorative properties, functioning primarily as a modulator of the Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) pathways. Semax demonstrates high stability in blood plasma and acts on the central nervous system to enhance cognitive function and regulate neuroinflammation. Research applications include investigations into ischemic stroke recovery, optic nerve health, and the modulation of dopaminergic and serotonergic neurotransmission.
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